Zepbound/Mounjaro (GIP and GLP-1)

Once-weekly Tirzepatide injection: Up to 22% average weight loss.

Ozempic (GLP-1)

Once-weekly semaglutide injection: Up to 16% average weight loss.

Wegovy (GLP-1)

Once-weekly Semaglutide injection: Up to 15% average weight loss.

Bupropion

Once-daily pill: Up to 10% weight loss.

Rybelsus (GLP-1)

Once-daily semaglutide pill: Up to 5% or more weight loss.